MOTS-cPremixedPen

The MOTS-c pre-mixed pen in Canada is supplied by Horizon Peptides as a 60 mg research pen, available singly or in 3-pen and 5-pen packs. MOTS-c is a mitochondrial-derived peptide studied in laboratory models of metabolic signalling.

MOTS-c is unusual in origin: it is encoded not in the cell nucleus but in mitochondrial DNA, making it one of a small group of mitochondrial-derived peptides. Its sequence is Met-Arg-Trp-Glu-Met-Glu-Val-Val-Arg-Ser-Gln-Arg, with a molecular weight of 1213.32.

That origin is the main reason it attracts research attention. Peptides encoded by the mitochondrial genome were not widely recognised until relatively recently, and MOTS-c is among the most studied examples, which makes it a common starting point for laboratories entering that field.

The pen supplies the peptide already in solution at a fixed concentration, which suits laboratories running repeated comparisons where preparation consistency matters. Where a study instead needs to set its own concentration, the lyophilized vial is the more suitable format.

At 60 mg the pen carries a larger quantity than either vial size, which lends itself to extended runs rather than single experiments.