{"product_id":"tirzepatide","title":"Tirzepatide","description":"\u003cp\u003eTirzepatide is supplied as lyophilized powder in sealed vials, in 5mg, 10mg and 15mg. Available as 1 vial, 3 vials or a 10-pack. Supplied strictly for research use only.\u003c\/p\u003e\n\u003ch2\u003eOverview\u003c\/h2\u003e\n\u003cp\u003eTirzepatide in Canada is supplied by Horizon Peptides as a lyophilized powder in sealed research vials, stocked in 5 mg, 10 mg and 15 mg sizes with single-vial, 3-vial and 10-vial pack options. Tirzepatide is a synthetic dual-receptor peptide studied in metabolic signalling research.\u003c\/p\u003e\n\u003cp\u003eTirzepatide is a long synthetic sequence with a molecular weight of 4813.0, the heaviest metabolic peptide stocked here. It carries Aib residues, a non-standard amino acid introduced specifically to resist enzymatic cleavage at positions where natural sequences are cut first.\u003c\/p\u003e\n\u003cp\u003eIts defining characteristic in the literature is acting at two receptor families rather than one, GLP-1 and GIP. Designing a single molecule to engage two related but distinct receptors is a harder problem than targeting either alone, and much of the research interest lies in how that dual engagement is achieved structurally.\u003c\/p\u003e\n\u003cp\u003eLaboratory work using it concerns receptor binding ratios between the two families, and comparison against single-receptor sequences to establish what the second interaction contributes.\u003c\/p\u003e\n\u003ch2\u003eKey research areas\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eDual GLP-1 and GIP receptor binding assays\u003c\/li\u003e\n\u003cli\u003eReceptor engagement ratio characterisation\u003c\/li\u003e\n\u003cli\u003eAib substitution and enzymatic resistance research\u003c\/li\u003e\n\u003cli\u003eComparative work against single-receptor analogues\u003c\/li\u003e\n\u003cli\u003eLong synthetic sequence purity characterisation\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e lyophilized powder in a sealed research vial\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSizes available:\u003c\/strong\u003e 5mg, 10mg, and 15mg\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePack options:\u003c\/strong\u003e 1 vial, 3 vials, or 10 pack\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular formula:\u003c\/strong\u003e C225H348N48O68\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular weight:\u003c\/strong\u003e 4813.0\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence:\u003c\/strong\u003e H-D-Aib-Glu-Glu-Glu-Glu-Glu-Aib-Ser-Gln-Tyr-Leu-Leu-Lys-Asp-Phe-Arg\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eComparable metabolic research peptides\u003c\/h2\u003e\n\u003cp\u003eA single-receptor comparison compound is \u003ca href=\"\/products\/semaglutide\"\u003esemaglutide\u003c\/a\u003e, and a sequence described as engaging three receptor families is GLP-3 (RT), also stocked as a pre-mixed pen.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eWhich receptors does tirzepatide engage?\u003c\/h3\u003e\n\u003cp\u003eTwo families, GLP-1 and GIP, rather than one.\u003c\/p\u003e\n\u003ch3\u003eWhat vial sizes are carried?\u003c\/h3\u003e\n\u003cp\u003eThree: 5 mg, 10 mg and 15 mg.\u003c\/p\u003e","brand":"Horizon Peptides","offers":[{"title":"5mg \/ 1 Vial","offer_id":50810672283873,"sku":"HP-TIRZEPATIDE-5MG-1","price":59.99,"currency_code":"CAD","in_stock":false},{"title":"5mg \/ 3 Vials","offer_id":50810672316641,"sku":"HP-TIRZEPATIDE-5MG-3","price":149.99,"currency_code":"CAD","in_stock":true},{"title":"5mg \/ 10 Vials","offer_id":50810672349409,"sku":"HP-TIRZEPATIDE-5MG-10","price":419.9,"currency_code":"CAD","in_stock":true},{"title":"10mg \/ 1 Vial","offer_id":50810672382177,"sku":"HP-TIRZEPATIDE-10MG-1","price":99.99,"currency_code":"CAD","in_stock":true},{"title":"10mg \/ 3 Vials","offer_id":50810672414945,"sku":"HP-TIRZEPATIDE-10MG-3","price":254.99,"currency_code":"CAD","in_stock":true},{"title":"10mg \/ 10 Vials","offer_id":50810672447713,"sku":"HP-TIRZEPATIDE-10MG-10","price":699.9,"currency_code":"CAD","in_stock":true},{"title":"15mg \/ 1 Vial","offer_id":50810672480481,"sku":"HP-TIRZEPATIDE-15MG-1","price":139.99,"currency_code":"CAD","in_stock":true},{"title":"15mg \/ 3 Vials","offer_id":50810672513249,"sku":"HP-TIRZEPATIDE-15MG-3","price":356.99,"currency_code":"CAD","in_stock":true},{"title":"15mg \/ 10 Vials","offer_id":50810672546017,"sku":"HP-TIRZEPATIDE-15MG-10","price":979.9,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0859\/2182\/4993\/files\/hp-tirzepatide.webp?v=1791438990","url":"https:\/\/horizonpeptides.ca\/products\/tirzepatide","provider":"Horizon Peptides","version":"1.0","type":"link"}