{"product_id":"tb-500","title":"TB-500","description":"\u003cp\u003eTB-500 is supplied as lyophilized powder in sealed vials, in 10mg and 20mg. Available as 1 vial, 3 vials or a 10-pack. Supplied strictly for research use only.\u003c\/p\u003e\n\u003ch2\u003eOverview\u003c\/h2\u003e\n\u003cp\u003eTB-500 in Canada is supplied by Horizon Peptides as a lyophilized powder in sealed research vials, stocked in 10 mg and 20 mg sizes with single-vial, 3-vial and 10-vial pack options. TB-500 is a synthetic fragment of thymosin beta-4 studied in cell-migration research models.\u003c\/p\u003e\n\u003cp\u003eTB-500 reproduces an active region of thymosin beta-4, a 43-residue protein whose principal described role is binding actin, the structural filament protein of the cytoskeleton. The fragment stocked here carries a molecular weight of 4963.5.\u003c\/p\u003e\n\u003cp\u003eWorking from a fragment rather than the whole protein is the usual approach in this area. Thymosin beta-4 is large enough that attributing an observation to any particular region is difficult; a defined fragment narrows the question considerably.\u003c\/p\u003e\n\u003cp\u003eActin is among the most abundant proteins in eukaryotic cells, so a sequence that binds it sits close to a great deal of cellular machinery. That breadth is both the appeal of the fragment as a research tool and the reason results from it need careful controls.\u003c\/p\u003e\n\u003cp\u003eIt is paired with a second sequence in the \u003ca href=\"\/products\/bpc-157-tb-500\"\u003eBPC-157 and TB-500 blend\u003c\/a\u003e and its \u003ca href=\"\/products\/bpc-157-tb-500-nasal-spray\"\u003enasal spray\u003c\/a\u003e, and forms part of both the \u003ca href=\"\/products\/glow\"\u003eGlow\u003c\/a\u003e and \u003ca href=\"\/products\/klow\"\u003eKlow\u003c\/a\u003e blends.\u003c\/p\u003e\n\u003ch2\u003eKey research areas\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eActin binding and cytoskeletal reorganisation assays\u003c\/li\u003e\n\u003cli\u003eCell-migration research models\u003c\/li\u003e\n\u003cli\u003eProtein fragment structure-activity studies\u003c\/li\u003e\n\u003cli\u003eAngiogenic signalling research\u003c\/li\u003e\n\u003cli\u003eControl design for broadly interacting sequences\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e lyophilized powder in a sealed research vial\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSizes available:\u003c\/strong\u003e 10mg and 20mg\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePack options:\u003c\/strong\u003e 1 vial, 3 vials, or 10 pack\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular formula:\u003c\/strong\u003e C212H350N56O78\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular weight:\u003c\/strong\u003e 4963.5\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence:\u003c\/strong\u003e Ac-Ser-Asp-Lys-Pro-Glu-Lys-Lys-Phe-Phe-Pro-Phe-Glu-Phe-Gly-Lys-Leu-Lys\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eWhich protein does the fragment come from?\u003c\/h3\u003e\n\u003cp\u003eThymosin beta-4, a 43-residue actin-binding protein.\u003c\/p\u003e\n\u003ch3\u003eWhy work with a fragment instead of the whole protein?\u003c\/h3\u003e\n\u003cp\u003eA defined fragment makes it far easier to attribute an observation to a specific region of the sequence.\u003c\/p\u003e","brand":"Horizon Peptides","offers":[{"title":"10mg \/ 1 Vial","offer_id":50809339019489,"sku":"HP-TB500-10MG-1","price":99.99,"currency_code":"CAD","in_stock":true},{"title":"10mg \/ 3 Vials","offer_id":50809339052257,"sku":"HP-TB500-10MG-3","price":254.99,"currency_code":"CAD","in_stock":true},{"title":"10mg \/ 10 Vials","offer_id":50810678935777,"sku":"HP-TB500-10MG-10","price":699.9,"currency_code":"CAD","in_stock":true},{"title":"20mg \/ 1 Vial","offer_id":50810678968545,"sku":"HP-TB500-20MG-1","price":194.99,"currency_code":"CAD","in_stock":true},{"title":"20mg \/ 3 Vials","offer_id":50810679001313,"sku":"HP-TB500-20MG-3","price":467.99,"currency_code":"CAD","in_stock":true},{"title":"20mg \/ 10 Vials","offer_id":50810679034081,"sku":"HP-TB500-20MG-10","price":1169.9,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0859\/2182\/4993\/files\/hp-tb-500.webp?v=1791438990","url":"https:\/\/horizonpeptides.ca\/products\/tb-500","provider":"Horizon Peptides","version":"1.0","type":"link"}