{"product_id":"semaglutide","title":"Semaglutide","description":"\u003cp\u003eSemaglutide is supplied as lyophilized powder in sealed vials, in 10mg. Available as 1 vial, 3 vials or a 10-pack. Supplied strictly for research use only.\u003c\/p\u003e\n\u003ch2\u003eOverview\u003c\/h2\u003e\n\u003cp\u003eSemaglutide in Canada is supplied by Horizon Peptides as a lyophilized powder in sealed 10 mg research vials, available singly or in 3-vial and 10-vial packs. Semaglutide is a synthetic GLP-1 receptor analogue studied in metabolic receptor signalling research.\u003c\/p\u003e\n\u003cp\u003eSemaglutide is a GLP-1 analogue with a molecular weight of 4113.6. Like others in its class it incorporates Aib substitution to slow enzymatic breakdown, and it carries a fatty acid chain attached to the backbone.\u003c\/p\u003e\n\u003cp\u003eThat lipid attachment is the feature worth understanding. A fatty acid gives the peptide affinity for albumin, and binding to a large circulating protein keeps the sequence available far longer than the unmodified analogue. It is the same general strategy used in CJC-1295, applied to a different peptide family.\u003c\/p\u003e\n\u003cp\u003eResearch with it concerns GLP-1 receptor binding and the effect of acylation on peptide persistence, generally alongside sequences that engage more than one receptor for comparison.\u003c\/p\u003e\n\u003ch2\u003eKey research areas\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eGLP-1 receptor binding and selectivity assays\u003c\/li\u003e\n\u003cli\u003eAcylation and albumin-binding research\u003c\/li\u003e\n\u003cli\u003eAib substitution stability studies\u003c\/li\u003e\n\u003cli\u003eSingle-receptor versus multi-receptor comparisons\u003c\/li\u003e\n\u003cli\u003ePeptide half-life characterisation\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e lyophilized powder in a sealed research vial\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSize available:\u003c\/strong\u003e 10mg\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePack options:\u003c\/strong\u003e 1 vial, 3 vials, or 10 pack\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular formula:\u003c\/strong\u003e C187H291N45O59\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular weight:\u003c\/strong\u003e 4113.6\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence:\u003c\/strong\u003e H-Aib-Glu-Glu-Glu-Glu-Glu-Aib-Ser-Gln-Tyr-Leu-Leu-Lys-Asp-Phe-Arg\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eComparable metabolic research peptides\u003c\/h2\u003e\n\u003cp\u003eDual and multi-receptor comparison compounds include \u003ca href=\"\/products\/tirzepatide\"\u003etirzepatide\u003c\/a\u003e and GLP-3 (RT). A different peptide family using the same albumin-binding strategy is represented by \u003ca href=\"\/products\/cjc-1295\"\u003eCJC-1295 with DAC\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eWhat does the fatty acid chain do?\u003c\/h3\u003e\n\u003cp\u003eIt gives the peptide affinity for albumin, which extends how long the sequence remains available.\u003c\/p\u003e\n\u003ch3\u003eHow is the 10 mg vial sold?\u003c\/h3\u003e\n\u003cp\u003eOn its own, in a 3-vial pack, or in a 10 pack.\u003c\/p\u003e","brand":"Horizon Peptides","offers":[{"title":"10mg \/ 1 Vial","offer_id":50810687455457,"sku":"HP-SEMAGLUTIDE-10MG-1","price":79.99,"currency_code":"CAD","in_stock":true},{"title":"10mg \/ 3 Vials","offer_id":50810687488225,"sku":"HP-SEMAGLUTIDE-10MG-3","price":203.99,"currency_code":"CAD","in_stock":true},{"title":"10mg \/ 10 Vials","offer_id":50810687520993,"sku":"HP-SEMAGLUTIDE-10MG-10","price":559.9,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0859\/2182\/4993\/files\/hp-semaglutide.webp?v=1791438990","url":"https:\/\/horizonpeptides.ca\/products\/semaglutide","provider":"Horizon Peptides","version":"1.0","type":"link"}