{"product_id":"mots-c","title":"MOTS-c","description":"\u003cp\u003eMOTS-c is supplied as lyophilized powder in sealed vials, in 10mg and 40mg. Available as 1 vial, 3 vials or a 10-pack. Supplied strictly for research use only.\u003c\/p\u003e\n\u003ch2\u003eOverview\u003c\/h2\u003e\n\u003cp\u003eMOTS-c in Canada is supplied by Horizon Peptides as a lyophilized powder in sealed research vials, stocked in 10 mg and 40 mg sizes with single-vial, 3-vial and 10-vial pack options. MOTS-c is a mitochondrial-derived peptide studied in metabolic signalling research.\u003c\/p\u003e\n\u003cp\u003eMOTS-c is encoded in mitochondrial DNA rather than in the cell nucleus, which sets it apart from essentially every other sequence in this catalogue. Its twelve residues run Met-Arg-Trp-Glu-Met-Glu-Val-Val-Arg-Ser-Gln-Arg, with a molecular weight of 2174.6.\u003c\/p\u003e\n\u003cp\u003eMitochondria carry their own small genome, a remnant of the bacterial ancestry of the organelle, and for a long time it was assumed to encode only components of the respiratory machinery. Peptides like MOTS-c showed that assumption was incomplete.\u003c\/p\u003e\n\u003cp\u003eResearch using it concerns metabolic and glucose-handling signalling, and more broadly the question of how many other short open reading frames in the mitochondrial genome remain uncharacterised.\u003c\/p\u003e\n\u003ch2\u003eKey research areas\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eMitochondrial-derived peptide research\u003c\/li\u003e\n\u003cli\u003eMetabolic and glucose-handling signalling models\u003c\/li\u003e\n\u003cli\u003eMitochondrial genome open reading frame studies\u003c\/li\u003e\n\u003cli\u003eCellular energy regulation assays\u003c\/li\u003e\n\u003cli\u003eComparative work against nuclear-encoded metabolic peptides\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e lyophilized powder in a sealed research vial\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSizes available:\u003c\/strong\u003e 10mg and 40mg\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePack options:\u003c\/strong\u003e 1 vial, 3 vials, or 10 pack\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular formula:\u003c\/strong\u003e C101H152N28O22S2\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular weight:\u003c\/strong\u003e 2174.6\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence:\u003c\/strong\u003e Met-Arg-Trp-Glu-Met-Glu-Val-Val-Arg-Ser-Gln-Arg\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eOther MOTS-c formats and related research material\u003c\/h2\u003e\n\u003cp\u003eMOTS-c is also stocked as a \u003ca href=\"\/products\/mots-c-premixed-pen\"\u003epre-mixed pen\u003c\/a\u003e. Related metabolic research material includes \u003ca href=\"\/products\/nad\"\u003eNAD+\u003c\/a\u003e, \u003ca href=\"\/products\/5-amino-1mq\"\u003e5-Amino-1MQ\u003c\/a\u003e and \u003ca href=\"\/products\/ss-31\"\u003eSS-31\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eWhat makes MOTS-c unusual?\u003c\/h3\u003e\n\u003cp\u003eIt is encoded in mitochondrial DNA rather than in the cell nucleus.\u003c\/p\u003e\n\u003ch3\u003eWhat sizes are stocked?\u003c\/h3\u003e\n\u003cp\u003eVials are available in 10 mg and 40 mg, each singly, as a 3-vial pack, or as a 10 pack.\u003c\/p\u003e","brand":"Horizon Peptides","offers":[{"title":"10mg \/ 1 Vial","offer_id":50809341116641,"sku":"HP-MOTSC-10MG-1","price":64.99,"currency_code":"CAD","in_stock":true},{"title":"10mg \/ 3 Vials","offer_id":50809341149409,"sku":"HP-MOTSC-10MG-3","price":164.99,"currency_code":"CAD","in_stock":true},{"title":"10mg \/ 10 Vials","offer_id":50810669433057,"sku":"HP-MOTSC-10MG-10","price":454.9,"currency_code":"CAD","in_stock":true},{"title":"40mg \/ 1 Vial","offer_id":50810669465825,"sku":"HP-MOTSC-40MG-1","price":199.99,"currency_code":"CAD","in_stock":true},{"title":"40mg \/ 3 Vials","offer_id":50810669498593,"sku":"HP-MOTSC-40MG-3","price":509.99,"currency_code":"CAD","in_stock":true},{"title":"40mg \/ 10 Vials","offer_id":50810669531361,"sku":"HP-MOTSC-40MG-10","price":1199.9,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0859\/2182\/4993\/files\/hp-mots-c.webp?v=1791438984","url":"https:\/\/horizonpeptides.ca\/products\/mots-c","provider":"Horizon Peptides","version":"1.0","type":"link"}