{"product_id":"ll-37","title":"LL-37","description":"\u003cp\u003eLL-37 is supplied as lyophilized powder in sealed vials, in 5mg. Available as 1 vial, 3 vials or a 10-pack. Supplied strictly for research use only.\u003c\/p\u003e\n\u003ch2\u003eOverview\u003c\/h2\u003e\n\u003cp\u003eLL-37 in Canada is supplied by Horizon Peptides as a lyophilized powder in sealed 5 mg research vials, available singly or in 3-vial and 10-vial packs. LL-37 is a 37-residue human cathelicidin peptide studied in antimicrobial and immune-signalling research.\u003c\/p\u003e\n\u003cp\u003eLL-37 is the only human cathelicidin, released from a precursor protein called hCAP18. Its name comes from its length and its first two residues: 37 amino acids beginning with two leucines. At 4493.0 it is one of the heaviest sequences stocked.\u003c\/p\u003e\n\u003cp\u003eUnlike most peptides in this catalogue it is naturally occurring rather than designed, and it folds into an amphipathic helix, one face carrying charged residues and the other hydrophobic ones. That arrangement is what underlies its described membrane interactions.\u003c\/p\u003e\n\u003cp\u003eResearch attention spans two distinct areas: direct interaction with microbial membranes, and separate immune-signalling roles that do not depend on that activity. Keeping those two lines of enquiry apart is a recurring methodological problem in the literature.\u003c\/p\u003e\n\u003cp\u003eIts length also makes it demanding to synthesise to a consistent standard, which is why purity specification matters more here than for the short sequences stocked alongside it.\u003c\/p\u003e\n\u003ch2\u003eKey research areas\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAntimicrobial membrane interaction assays\u003c\/li\u003e\n\u003cli\u003eInnate immune signalling research\u003c\/li\u003e\n\u003cli\u003eAmphipathic helix structure and folding studies\u003c\/li\u003e\n\u003cli\u003eCathelicidin precursor processing research\u003c\/li\u003e\n\u003cli\u003eLong-sequence synthesis and purity characterisation\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e lyophilized powder in a sealed research vial\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSize available:\u003c\/strong\u003e 5mg\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePack options:\u003c\/strong\u003e 1 vial, 3 vials, or 10 pack\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular formula:\u003c\/strong\u003e C205H340N60O53\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular weight:\u003c\/strong\u003e 4493.0\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence:\u003c\/strong\u003e LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eRelated research peptides\u003c\/h2\u003e\n\u003cp\u003eOther immune-associated sequences in the catalogue include \u003ca href=\"\/products\/thymosin-alpha-1\"\u003eThymosin Alpha-1\u003c\/a\u003e, \u003ca href=\"\/products\/thymalin\"\u003eThymalin\u003c\/a\u003e and \u003ca href=\"\/products\/kpv\"\u003eKPV\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow long is the sequence?\u003c\/h3\u003e\n\u003cp\u003eThirty-seven residues, giving a molecular weight of 4493.0.\u003c\/p\u003e\n\u003ch3\u003eIs LL-37 naturally occurring?\u003c\/h3\u003e\n\u003cp\u003eYes. It is the only cathelicidin peptide found in humans, processed from the hCAP18 precursor.\u003c\/p\u003e","brand":"Horizon Peptides","offers":[{"title":"5mg \/ 1 Vial","offer_id":50810707706081,"sku":"HP-LL37-5MG-1","price":119.99,"currency_code":"CAD","in_stock":true},{"title":"5mg \/ 3 Vials","offer_id":50810707738849,"sku":"HP-LL37-5MG-3","price":299.99,"currency_code":"CAD","in_stock":true},{"title":"5mg \/ 10 Vials","offer_id":50810707771617,"sku":"HP-LL37-5MG-10","price":839.9,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0859\/2182\/4993\/files\/hp-ll-37.webp?v=1791438984","url":"https:\/\/horizonpeptides.ca\/products\/ll-37","provider":"Horizon Peptides","version":"1.0","type":"link"}