{"product_id":"igf-1-lr3","title":"IGF-1 LR3","description":"\u003cp\u003eIGF-1 LR3 is supplied as lyophilized powder in sealed vials, in 1mg. Available as 1 vial, 3 vials or a 10-pack. Supplied strictly for research use only.\u003c\/p\u003e\n\u003ch2\u003eOverview\u003c\/h2\u003e\n\u003cp\u003eIGF-1 LR3 in Canada is supplied by Horizon Peptides as a lyophilized powder in sealed 1 mg research vials, available singly or in 3-vial and 10-vial packs. IGF-1 LR3 is a modified insulin-like growth factor analogue studied in cell-culture growth research.\u003c\/p\u003e\n\u003cp\u003eIGF-1 LR3 is an engineered version of insulin-like growth factor 1, at a molecular weight of 9026.0 the largest molecule stocked in this catalogue by a wide margin. The LR3 designation encodes its two modifications: a 13-residue extension at one end, and arginine substituted at position 3.\u003c\/p\u003e\n\u003cp\u003eBoth changes serve one purpose. Native IGF-1 circulates bound to binding proteins that limit its availability, and the substitution at position 3 sharply reduces that binding. The molecule is essentially designed to escape its own regulatory system.\u003c\/p\u003e\n\u003cp\u003eThat property is exactly why it appears in cell-culture work: a growth factor that is not sequestered by binding proteins behaves far more predictably in a defined medium than the native form.\u003c\/p\u003e\n\u003ch2\u003eKey research areas\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eCell-culture growth supplementation research\u003c\/li\u003e\n\u003cli\u003eBinding protein affinity and escape modification studies\u003c\/li\u003e\n\u003cli\u003eInsulin-like growth factor receptor assays\u003c\/li\u003e\n\u003cli\u003eProtein engineering and sequence extension research\u003c\/li\u003e\n\u003cli\u003eComparative work against native IGF-1\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e lyophilized powder in a sealed research vial\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSize available:\u003c\/strong\u003e 1mg\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePack options:\u003c\/strong\u003e 1 vial, 3 vials, or 10 pack\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular formula:\u003c\/strong\u003e C134H228N40O41\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular weight:\u003c\/strong\u003e 9026.0\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence:\u003c\/strong\u003e Gly-Ala-Gln-Leu-Arg-Lys-Asp-Ile-Ile-Leu-Gln-Ala-Val-Gly-Glu-Leu-Cys-Ala-Leu-Val-Gly-Ser-Arg-Leu-Leu\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eRelated research material\u003c\/h2\u003e\n\u003cp\u003eAnother growth hormone fragment stocked here is \u003ca href=\"\/products\/aod-9604\"\u003eAOD-9604\u003c\/a\u003e. Sequences studied around growth hormone signalling include \u003ca href=\"\/products\/cjc-1295\"\u003eCJC-1295 with DAC\u003c\/a\u003e and \u003ca href=\"\/products\/sermorelin\"\u003eSermorelin\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eWhat does LR3 stand for?\u003c\/h3\u003e\n\u003cp\u003eLong R3: a 13-residue extension at one end, and arginine substituted at position 3.\u003c\/p\u003e\n\u003ch3\u003eWhat size is the vial?\u003c\/h3\u003e\n\u003cp\u003e1 mg, available singly, in a 3-vial pack, or in a 10 pack.\u003c\/p\u003e","brand":"Horizon Peptides","offers":[{"title":"1mg \/ 1 Vial","offer_id":50810689552609,"sku":"HP-IGF1LR3-1MG-1","price":104.99,"currency_code":"CAD","in_stock":true},{"title":"1mg \/ 3 Vials","offer_id":50810689585377,"sku":"HP-IGF1LR3-1MG-3","price":267.99,"currency_code":"CAD","in_stock":true},{"title":"1mg \/ 10 Vials","offer_id":50810689618145,"sku":"HP-IGF1LR3-1MG-10","price":734.9,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0859\/2182\/4993\/files\/hp-igf-1-lr3.webp?v=1791438962","url":"https:\/\/horizonpeptides.ca\/products\/igf-1-lr3","provider":"Horizon Peptides","version":"1.0","type":"link"}