{"product_id":"ara-290","title":"ARA-290","description":"\u003cp\u003eARA-290 is supplied as lyophilized powder in sealed vials, in 10mg. Available as 1 vial, 3 vials or a 10-pack. Supplied strictly for research use only.\u003c\/p\u003e\n\u003ch2\u003eOverview\u003c\/h2\u003e\n\u003cp\u003eARA-290 in Canada is supplied by Horizon Peptides as a lyophilized powder in sealed 10 mg research vials, available singly or in 3-vial and 10-vial packs. ARA-290 is a synthetic erythropoietin-derived peptide studied in tissue-protection signalling research.\u003c\/p\u003e\n\u003cp\u003eARA-290, also catalogued as cibinetide, is an eleven-residue peptide derived from a region of erythropoietin. Erythropoietin is best known as the hormone governing red blood cell production, but the fragment reproduced here corresponds to a structurally distinct part of the molecule.\u003c\/p\u003e\n\u003cp\u003eThat distinction is the point. The described tissue-protective signalling attributed to erythropoietin is associated with a different receptor arrangement than its haematopoietic role, and a fragment that maps to one and not the other allows the two to be examined separately.\u003c\/p\u003e\n\u003cp\u003eSeparating two roles carried by one parent molecule is among the harder problems in this field, because any effect seen with the intact hormone could belong to either. A fragment that reaches only one of them turns an ambiguous result into a clean one.\u003c\/p\u003e\n\u003cp\u003eResearch using it concerns the innate repair receptor and tissue-protection pathways in animal and cell models, generally with the intact hormone as a comparison arm.\u003c\/p\u003e\n\u003ch2\u003eKey research areas\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eInnate repair receptor signalling research\u003c\/li\u003e\n\u003cli\u003eErythropoietin fragment structure-activity studies\u003c\/li\u003e\n\u003cli\u003eSeparation of dual-role hormone pathways\u003c\/li\u003e\n\u003cli\u003eTissue-protection models in cell culture\u003c\/li\u003e\n\u003cli\u003eFragment-versus-parent hormone comparisons\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e lyophilized powder in a sealed research vial\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSize available:\u003c\/strong\u003e 10mg\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePack options:\u003c\/strong\u003e 1 vial, 3 vials, or 10 pack\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eRelated fragment-derived research peptides\u003c\/h2\u003e\n\u003cp\u003eOther sequences reproducing part of a larger protein include \u003ca href=\"\/products\/aod-9604\"\u003eAOD-9604\u003c\/a\u003e and \u003ca href=\"\/products\/tb-500\"\u003eTB-500\u003c\/a\u003e. An immune-associated fragment stocked here is \u003ca href=\"\/products\/thymosin-alpha-1\"\u003eThymosin Alpha-1\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eWhat is ARA-290 derived from?\u003c\/h3\u003e\n\u003cp\u003eA region of erythropoietin, distinct from the part associated with red blood cell production.\u003c\/p\u003e\n\u003ch3\u003eWhy use a fragment rather than the whole hormone?\u003c\/h3\u003e\n\u003cp\u003eBecause the parent molecule carries more than one described role, and a fragment can reach only one of them.\u003c\/p\u003e","brand":"Horizon Peptides","offers":[{"title":"10mg \/ 1 Vial","offer_id":50810703053025,"sku":"HP-ARA290-10MG-1","price":74.99,"currency_code":"CAD","in_stock":true},{"title":"10mg \/ 3 Vials","offer_id":50810703085793,"sku":"HP-ARA290-10MG-3","price":191.99,"currency_code":"CAD","in_stock":true},{"title":"10mg \/ 10 Vials","offer_id":50810703118561,"sku":"HP-ARA290-10MG-10","price":524.9,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0859\/2182\/4993\/files\/hp-ara-290.webp?v=1791438954","url":"https:\/\/horizonpeptides.ca\/products\/ara-290","provider":"Horizon Peptides","version":"1.0","type":"link"}