{"title":"Tanning","description":null,"products":[{"product_id":"melanotan-ii-mt-2","title":"MT-2 (Melanotan II)","description":"\u003cp\u003eMT-2 (Melanotan II) is supplied as lyophilized powder in sealed vials, in 10mg. Available as 1 vial, 3 vials or a 10-pack. Supplied strictly for research use only.\u003c\/p\u003e\n\u003ch2\u003eOverview\u003c\/h2\u003e\n\u003cp\u003eMT-2, also catalogued as Melanotan II, in Canada is supplied by Horizon Peptides as a lyophilized powder in sealed 10 mg research vials, available singly or in 3-vial and 10-vial packs. MT-2 is a synthetic cyclic melanocortin analogue used in receptor research.\u003c\/p\u003e\n\u003cp\u003eMT-2 is a cyclic peptide, Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH, at 1025.2. The square brackets in that notation mark the ring: a bond joins two side chains, closing part of the backbone into a loop rather than leaving it as an open chain.\u003c\/p\u003e\n\u003cp\u003eConstraining a peptide into a ring restricts the shapes it can adopt. For receptor research that is valuable, because a molecule locked into fewer conformations gives more interpretable binding data than a flexible chain that samples many.\u003c\/p\u003e\n\u003cp\u003eIt binds across several melanocortin receptor subtypes rather than selecting sharply between them, which is precisely why it is used as a broad reference compound in the field.\u003c\/p\u003e\n\u003ch2\u003eKey research areas\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eMelanocortin receptor subtype binding assays\u003c\/li\u003e\n\u003cli\u003eCyclic peptide conformational restriction research\u003c\/li\u003e\n\u003cli\u003eReference-compound use in receptor panels\u003c\/li\u003e\n\u003cli\u003eMelanogenesis pathway models in cell culture\u003c\/li\u003e\n\u003cli\u003eComparative work against linear alpha-MSH fragments\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e lyophilized powder in a sealed research vial\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSize available:\u003c\/strong\u003e 10mg\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePack options:\u003c\/strong\u003e 1 vial, 3 vials, or 10 pack\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular formula:\u003c\/strong\u003e C50H69N15O9\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular weight:\u003c\/strong\u003e 1025.2\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence:\u003c\/strong\u003e Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eOther MT-2 formats and related analogues\u003c\/h2\u003e\n\u003cp\u003eThe same analogue is stocked as a \u003ca href=\"\/products\/melanotan-2-nasal-spray\"\u003eMelanotan 2 nasal spray\u003c\/a\u003e. The earlier linear analogue is \u003ca href=\"\/products\/mt-1-melanotan-i\"\u003eMT-1\u003c\/a\u003e, and a receptor-selective relative is \u003ca href=\"\/products\/pt-141\"\u003ePT-141\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eWhat does the cyclic notation mean?\u003c\/h3\u003e\n\u003cp\u003eThe bracketed residues form a ring, closed by a bond between two side chains.\u003c\/p\u003e\n\u003ch3\u003eWhat sizes are stocked?\u003c\/h3\u003e\n\u003cp\u003eThe 10 mg vial is sold on its own, in a 3-vial pack, or in a 10 pack.\u003c\/p\u003e","brand":"Horizon Peptides","offers":[{"title":"10mg \/ 1 Vial","offer_id":50810676838625,"sku":"HP-MELANOTANIIMT2-10MG-1","price":59.99,"currency_code":"CAD","in_stock":true},{"title":"10mg \/ 3 Vials","offer_id":50810676871393,"sku":"HP-MELANOTANIIMT2-10MG-3","price":149.99,"currency_code":"CAD","in_stock":true},{"title":"10mg \/ 10 Vials","offer_id":50810676904161,"sku":"HP-MELANOTANIIMT2-10MG-10","price":419.9,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0859\/2182\/4993\/files\/hp-melanotan-ii-mt-2.webp?v=1791438984"},{"product_id":"mt-1-melanotan-i","title":"MT-1 (Melanotan I)","description":"\u003cp\u003eMT-1 (Melanotan I) is supplied as lyophilized powder in sealed vials, in 10mg. Available as 1 vial, 3 vials or a 10-pack. Supplied strictly for research use only.\u003c\/p\u003e\n\u003ch2\u003eOverview\u003c\/h2\u003e\n\u003cp\u003eMT-1, also catalogued as Melanotan I, in Canada is supplied by Horizon Peptides as a lyophilized powder in sealed 10 mg research vials, available singly or in 3-vial and 10-vial packs. MT-1 is a melanocortin analogue studied in pigmentation pathway research.\u003c\/p\u003e\n\u003cp\u003eMT-1 is the first-generation Melanotan analogue, predating the cyclic compound that followed it. The catalogue records a molecular weight of 1646.8 for the material supplied here.\u003c\/p\u003e\n\u003cp\u003eIts interest as a research tool lies almost entirely in that chronology. When a second-generation compound is developed to address limitations in the first, keeping the original available lets researchers test whether the intended improvement actually shows up in binding data, rather than taking the design rationale on trust.\u003c\/p\u003e\n\u003cp\u003eStudies using it concern melanocortin receptor interaction and melanogenesis pathways in cell-culture systems, generally as one arm of a comparison rather than in isolation.\u003c\/p\u003e\n\u003cp\u003eThe second-generation compound is \u003ca href=\"\/products\/melanotan-ii-mt-2\"\u003eMT-2\u003c\/a\u003e, also available as a \u003ca href=\"\/products\/melanotan-2-nasal-spray\"\u003enasal spray\u003c\/a\u003e. A further member of the melanocortin family stocked here is \u003ca href=\"\/products\/pt-141\"\u003ePT-141\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eKey research areas\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eFirst-generation analogue characterisation\u003c\/li\u003e\n\u003cli\u003eGenerational comparison within an analogue series\u003c\/li\u003e\n\u003cli\u003eMelanocortin receptor interaction assays\u003c\/li\u003e\n\u003cli\u003eMelanogenesis pathway models in cell culture\u003c\/li\u003e\n\u003cli\u003eDesign-rationale validation studies\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e lyophilized powder in a sealed research vial\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSize available:\u003c\/strong\u003e 10mg\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePack options:\u003c\/strong\u003e 1 vial, 3 vials, or 10 pack\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular formula:\u003c\/strong\u003e C78H111N21O19\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular weight:\u003c\/strong\u003e 1646.8\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eWhat distinguishes MT-1 from the later analogue?\u003c\/h3\u003e\n\u003cp\u003eMT-1 is the original compound in the series; the later one was developed afterwards with a modified structure.\u003c\/p\u003e\n\u003ch3\u003eIs MT-1 usually studied on its own?\u003c\/h3\u003e\n\u003cp\u003eMore often as one arm of a comparison against the second-generation analogue.\u003c\/p\u003e","brand":"Horizon Peptides","offers":[{"title":"10mg \/ 1 Vial","offer_id":50810685358305,"sku":"HP-MT1MELANOTANI-10MG-1","price":59.99,"currency_code":"CAD","in_stock":true},{"title":"10mg \/ 3 Vials","offer_id":50810685391073,"sku":"HP-MT1MELANOTANI-10MG-3","price":149.99,"currency_code":"CAD","in_stock":true},{"title":"10mg \/ 10 Vials","offer_id":50810685423841,"sku":"HP-MT1MELANOTANI-10MG-10","price":419.9,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0859\/2182\/4993\/files\/hp-mt-1-melanotan-i.webp?v=1791438984"},{"product_id":"melanotan-2-nasal-spray","title":"Melanotan 2 Nasal Spray","description":"\u003cp\u003eMelanotan 2 Nasal Spray is supplied ready-mixed in a metered nasal spray bottle, 10mg (166mcg\/spray). Available as 1, 3 or 5 spray bottles. Supplied strictly for research use only.\u003c\/p\u003e\n\u003ch2\u003eOverview\u003c\/h2\u003e\n\u003cp\u003eMelanotan 2 nasal spray in Canada is supplied by Horizon Peptides as a pre-prepared 10 mg research spray bottle, available singly or in 3-bottle and 5-bottle packs. Melanotan 2 is a synthetic cyclic analogue of alpha-melanocyte-stimulating hormone studied in melanocortin receptor research.\u003c\/p\u003e\n\u003cp\u003eMelanotan 2 is a cyclic peptide, Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH, with a molecular weight of 1025.2. The ring structure is the defining feature: closing the backbone into a ring constrains its shape and slows enzymatic breakdown compared with the linear hormone fragment it is modelled on.\u003c\/p\u003e\n\u003cp\u003eBecause it is shorter and more stable than natural alpha-MSH, it is widely used as a reference compound in melanocortin receptor binding studies, where a consistent, well-characterised analogue is more practical than the parent hormone.\u003c\/p\u003e\n\u003cp\u003eIts stability relative to the natural hormone is the practical reason it appears so often in receptor work. A compound that persists through an assay gives cleaner comparative data than one degrading over the same period.\u003c\/p\u003e\n\u003ch2\u003eKey research areas\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eMelanocortin receptor binding and selectivity assays\u003c\/li\u003e\n\u003cli\u003eCyclic peptide conformation and stability research\u003c\/li\u003e\n\u003cli\u003eMelanogenesis pathway models in cell culture\u003c\/li\u003e\n\u003cli\u003eComparative studies against linear alpha-MSH fragments\u003c\/li\u003e\n\u003cli\u003eStructure-activity work across melanocortin analogues\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e pre-prepared liquid in a research spray bottle\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSize available:\u003c\/strong\u003e 10mg (166mcg\/spray)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePack options:\u003c\/strong\u003e 1 spray bottle, 3 spray bottles, or 5 spray bottles\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eOther Melanotan formats and related research peptides\u003c\/h2\u003e\n\u003cp\u003eThe same analogue is stocked as the \u003ca href=\"\/products\/melanotan-ii-mt-2\"\u003eMT-2 lyophilized vial\u003c\/a\u003e. The related first-generation analogue is available as \u003ca href=\"\/products\/mt-1-melanotan-i\"\u003eMT-1\u003c\/a\u003e, and a further melanocortin sequence is stocked as \u003ca href=\"\/products\/pt-141\"\u003ePT-141\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eHow much Melanotan 2 is in each bottle?\u003c\/h3\u003e\n\u003cp\u003eEach spray bottle contains 10 mg.\u003c\/p\u003e\n\u003ch3\u003eIs this the same compound as the MT-2 vial?\u003c\/h3\u003e\n\u003cp\u003eYes. Both contain the same cyclic analogue; only the presentation differs.\u003c\/p\u003e","brand":"Horizon Peptides","offers":[{"title":"10mg \/ 1 Spray Bottle","offer_id":50810705477857,"sku":"HP-MELANOTAN2NASALSPR-10MG-1","price":119.99,"currency_code":"CAD","in_stock":true},{"title":"10mg \/ 3 Spray Bottles","offer_id":50810705510625,"sku":"HP-MELANOTAN2NASALSPR-10MG-3","price":299.99,"currency_code":"CAD","in_stock":true},{"title":"10mg \/ 5 Spray Bottles","offer_id":50810705543393,"sku":"HP-MELANOTAN2NASALSPR-10MG-5","price":399.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0859\/2182\/4993\/files\/hp-melanotan-2-nasal-spray.webp?v=1791438984"}],"url":"https:\/\/horizonpeptides.ca\/collections\/tanning.oembed","provider":"Horizon Peptides","version":"1.0","type":"link"}